After the events of The Guardians of the Galaxy Holiday Special, Peter Quill and his band of misfits embark on a perilous task to save their friend Rocket from certain death after an attack by the mysterious Adam Warlock. Their quest has them cross paths with the High Evolutionary, allowing him to set his sights on the Guardians and his most prized experiment, Rocket.
- Knowhere – Guardians of the Galaxy HQ – M21I R516XS16C+16151MW
- The Orgoscope – OrgoCorp HQ – A41P P2326Y430+174144V
- Counter-Earth – K20H MW1748P2S+5M5P0Z4
- Jason Quill House, St Louis
- Krylor Desert
Guardians of the Galaxy, Vol. 3 was shot at Trilith Studios in Fayetteville, GA, and in the Atlanta area.